People
TRIDENT involves eight core teams of world-class researchers and highly qualified personnel across four leading academic institutions. The expertise and infrastructure represented in TRIDENT cannot be replicated and is truly one-of-a-kind, and does not exist anywhere else in the world.
Administration
Administrative Core
TRIDENT believes robust administrative support is critical to efficient research operations and collaboration. TRIDENT has a team of highly skilled staff to provide assistance across all of the research Cores and to facilitate streamlined partnership engagement.
Research Cores
iPSC/Organoid Core
The TRIDENT iPSC/Organoid Core is based at McGill University, in partnership with the Montreal Neurological Institute-Hospital’s (The Neuro) Early Drug Discovery Unit (EDDU).
Mouse Core
The TRIDENT Mouse Core involves teams at McGill University, Western University and the University of Toronto,
Marmoset Core
The Marmoset Core model development and imaging. The Marmoset Core comprises of teams at both Western and McGill Universities.
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Data Management and Sharing Core
A unique feature of the TRIDENT platform is the integration of research data and findings across different species, multiple research sites, and data modalities. TRIDENT follows a sophisticated and robust data management plan that ensures rigorous data and meta-data standards to promote accessibility, interoperability, and reusability for all concerned parties.
Open Science, Practices and Partnerships Core
TRIDENT introduces an innovative paradigm for conducting pre-clinical research using an open science and living lab framework.
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Sex-Based Analysis+ Core
The TRIDENT SBA+ core is led by a Canadian team of researchers that advises on how to effectively incorporate sex, and other aging-related hormonal milieu differences into the research study design and analysis at every stage of the platform to evaluate neurotherapeutics to improve the translational potential of this unique pre-clinical platform. This includes a better understanding of cognitive processes and emotional control in healthy brains, as well as the development of better precision therapeutics for neurodegenerative and psychiatric disorders.
Advisory Groups
TRIDENT is governed and administered using a horizontal, consensus-driven management structure to promotetrans- and interdisciplinary practices.
