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Marmoset

Marmoset
Core

The drugs that pass the Mouse Core then land on the TRIDENT Marmoset Core - the final stage in neurotherapeutic validation.  The TRIDENT Marmoset Core is currently developing marmoset disease models that can faithfully recapitulate complex human brain disorders, thereby providing a powerful model not only to study the pathophysiology of neurodegenerative diseases but also to test the efficacy of neurotherapeutics in a model that is a close relative to humans.  Drugs that pass this final stage of the TRIDENT platform are regarded as robustly de-risked and will have a near guarantee of success in clinical trials.

The TRIDENT Marmoset Core is proficient in generating developmental and disease models of non-human primates , specifically marmosets. Further, using their extensive expertise in brain imaging and neurophysiological approaches, they are uniquely poised to uncover how the central and peripheral nervous systems become dysfunctional in disease, using an animal model that is phylogenetically proximal, neuroanatomically, and genetically similar to humans.

TRIDENT is committed to the highest standards of care for animals in research. 

Current Models

α-synucleinopathy

MEET THE TEAM

Dr. Justine Clery headshot
DR. JUSTINE CLERY

TRIDENT Co-Principal Investigator
and Marmoset Team Lead

Assistant Professor, Department of Neurology and Neurosurgery,
McGill University

Head of the Sensory and Social Brain Mechanisms (SSBM) Lab at The Neuro,
McGill University


Email: 

justine.clery@mcgill.ca

​​

Website:
https://www.mcgill.ca/neuro/justine-clery-phd
​​
 

Dr. Stefan Everling headshot
DR. STEFAN EVERLING

TRIDENT Co-Principal Investigator
and Marmoset Team Lead


Professor of Physiology and Pharmacology, Western University

Scientist at the Robarts Research Institute at the University of Western Ontario.

 

Email: 

severlin@uwo.ca

 

​​Website:

http://www.everling-lab.org/stefan-everling.html

​

Dr. Ravi Menon headshot
DR. RAVI MENON

TRIDENT Principal Investigator
and Imaging Biomarker Team Lead


Professor, Departments of Medical Biophysics, Medical Imaging, Neuroscience, and Psychiatry, Western University


Canada Research Chair in Functional and Molecular Imaging

 

Research Scientist, CFMM

Co-Scientific Director of BrainsCAN


​Email: 

rmenon@uwo.ca

​​

Website:
https://cfmm.uwo.ca/people/core_scientists/ravi_menon.html

Dr. Marco Prado headshot
DR. MARCO PRADO


TRIDENT Co-Principal Investigator
and Molecular Biomarker Team Lead

Professor, Department of Physiology and
Pharmacology and Department of Anatomy
& Cell Biology

Scientist, Robarts Research Institute

Canada Research Chair in Neurochemistry
of Dementia

 

Deputy Editor in Chief Journal of Neurochemistry

Email: 

mprado@uwo.ca​​

 

​Website:

https://www.schulich.uwo.ca/physpharm//people/faculty/prado_marco.html

​

​

Highly Qualified Personnel

Tyler Cook headshot

Tyler Cook

Graduate Student
McGill University

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Hannah Pettypiece

Technician
Western University

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Constance Dollet

Research Assistant
McGill University

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Jesleen Saini

Graduate Student
Western University

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David Everling

Research Assistant
Western University

Jiayue Yang headshot

Jiayue Yang

Graduate Student

McGill University

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Maeva Gacoin

Postdoctoral Fellow
McGill University

Alessandro Zanini headshot

Alessandro Zanini

Postdoctoral Fellow

Western University

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